Conference Proceedings
How patients with neuromyelitis optica spectrum disorder accumulate disability
Sifat Sharmin, Izanne Roos, Pakeeran Siriratnam, Serkan Ozakbas, Dana Horakova, Eva Havrdova, Recai Turkoglu, Francesco Patti, Bassem I Yamout, Samia Khoury, Abdullah Al-Asmi, Guy Laureys, Liesbeth Van Hijfte, Raed Alroughani, Jeannette Lechner-Scott, Murat Terzi, Cavit Boz, Ayse Altintas, Vahid Shaygannejad, Aysun Soysal Show all
MULTIPLE SCLEROSIS JOURNAL | SAGE PUBLICATIONS LTD | Published : 2024
Abstract
BACKGROUND: It is believed that patients with neuromyelitis optica spectrum disease acquire disability exclusively through relapses. However, the possibility of disability accumulation in the absence of relapses has also been suggested. We quantified irreversible disability accumulation in the presence and absence of relapses in neuromyelitis optica spectrum disease. METHODS: We identified patients with neuromyelitis optica spectrum disease in the MSBase registry. Disability-worsening events were required to be sustained until the end of follow-up. Worsening in the absence of relapses was validated through primary record review. RESULTS: Over 884 patient-years of follow-up, we identified 32 ..
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Awarded by MSBase Foundation
Awarded by National Health and Medical Research Council